Santiago Eneme is a 26-year-old professional football player from GEQ. He currently plays for Sparta Praha, wearing the number 5 shirt. At the international level, he represents Equatorial Guinea. He plays primarily as a Midfield. He stands at 183cm tall and weighs 65kg. His current market value is estimated at 2M €.

His most recent move was a Free from Slovan Liberec to Sparta Praha on 2025-07-01. The reported fee was 2M €.

Across 19 appearances in the Czech Chance Liga 2025-2026, Santiago Eneme registered 0 goals and 0 assists, while completing 8 key passes out of 185 total passes with a passing accuracy of 8.4.